激酶抑制剂与调节剂
激酶与磷酸化通路的抑制剂、激活剂及调节剂。
-
HY-111378ACasein Kinase II Inhibitor IV hydrochloride 2320347-54-2
Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation.
-
HY-110367ALCB 03-0110 1228102-01-9
LCB 03-0110, a thienopyridine derivative, is a potent pan-discoidin domain receptor/c-Src family tyrosine kinase...
-
HY-W674387Nec-34i 2212541-00-7
Nec-34i is an inactive analog structurally similar to Nec-34 ( HY-132203 ). Nec-34i has no effect on RIPK1 kinase...
-
HY-18651(E/Z)-Rigosertib sodium 1225497-78-8
Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for...
-
HY-121998Binucleine 2 220088-42-6
Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki=0.36 μM), a...
-
HY-116138RG-14467 137515-05-0
RG-14467 is an epidermal growth factor receptor tyrosine kinase inhibitor with activity that inhibits enzyme...
-
HY-114667Lavendustin C6 144676-04-0
Lavendustin C6 is a specific inhibitor of tyrosine kinase . Lavendustin C6 inhibits epidermal growth factor ( EGF )...
-
HY-112395BTO-1 40647-02-7
BTO-1 is a Polo-like kinase ( Plk ) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation...
-
HY-W064657Momelotinib dihydrochloride 1380317-28-1
Momelotinib (dihydrochloride) is a JAK1/JAK2 inhibitor that also antagonizes ACVR1 , leading to downregulation of...
-
HY-121792CK2-IN-1 51726-83-1
CK2-IN-1 is a CK2 inhibitor, with an IC 50 of 150 nM.
-
HY-121634DAP-81 794466-17-4
DAP-81 is an inhibitory agent targeting Polo-like kinases (Plks), a class of evolutionarily conserved...
-
HY-120857BPIQ-II hydrochloride 171179-37-6
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth...
-
HY-119177PD173956 305820-76-2
PD173956 is a pyridopyrimidine Bcr-Abl kinase inhibitor with high selectivity for the P-loop mutant form of Bcr-Abl .
-
HY-116559TIBI 1196457-06-3
TIBI is a potent and ATP-competitive inhibitor of Rio1 ( IC 50 : 0.09 μM, K i : 0.05 μM). TIBI enhances the...
-
HY-118964Tyrphostin AG 568 151013-48-8
Tyrphostin AG 568 is a tyrphostin tyrosine kinase inhibitor that induces erythroid differentiation. Tyrphostin AG...
-
HY-118175RG 14921 144909-21-7
RG 14921 is a compound structurally related to Erbstatin ( HY-113549 ) and has inhibitory activity against EGFR...
-
HY-118131PKR-IN-C51 1314594-23-4
PKR-IN-C51 is an ATP-competitive protein kinase R (PKR) inhibitor with a human IC 50 of 9 μM and a human K i of 3.4...
-
HY-113599Isoprocurcumenol 102130-90-5
Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa . Isoprocurcumenol can...
-
HY-112094WNK-IN-11 2123489-30-3
WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC 50 of 4 nM for WNK1 .
-
HY-W0426484,5,6,7-Tetrabromo-1H-benzimidazole 577779-57-8
4,5,6,7-Tetrabromobenzimidazole is a selective and ATP competitive CK2 ( casein kinase 2) inhibitor.