RGH-706 is an orally active, blood-brain barrier-permeable, selective MCH1 receptor antagonist with an IC 50 of 6.2 nM against hMCHR1. RGH-706 shows no antagonistic activity against h MCH2 receptors. RGH-706 improves obesity. RGH-706 can be used in research related to obesity and Prader-Willi syndrome.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > MCHR1 (GPR24)
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