FP1-24

Overview

FP1-24 is a non-selective CK1 kinase inhibitor, with IC 50 values of 40 nM, 10 nM, 10 nM, and 40 nM against human CK1γ1, CK1γ2, CK1γ3 and CK1δ , respectively. FP1-24 exerts its activity by reducing the phosphorylation level of LRP5/6 at the T1479 site during WNT signaling pathway activation. The non-specific binding of FP1-24 to multiple kinases can be used for biological studies of specific CK1γ .

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Others | Products > Signaling Pathways > Casein Kinase

Product Information

• Catalog No.: HY-181585
• CAS No.: 1403557-08-3
• Molecular Formula: C20H17F2N3O3
• Molecular Weight: 385.36
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source