Other bioactive inhibitors, agonists, antagonists and pathway modulators.
Introduction Clascoterone is an antagonist of androgen receptors used for topical treatment of acne
Exatecan CAS:171335-80-1 is an innovative camptothecin (CPT) analog that demonstrates powerful topoisomerase-I...
Eribulin Mesylate (CAS: 441045-17-6) is a potent microtubule-targeting agent and synthetic analog of halichondrin B....
Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active...
TAPS is an aminosulfonate-based lysozyme stabilizer and connexin channel inhibitor. TAPS maintains the native...
Sphingomyelin, a major cell membrane component, is highly concentrated in nerve cell myelin sheaths and red blood...
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48.
Irinotecan((+)-Irinotecan) CAS:97682-44-5, is a potent topoisomerase I inhibitor that plays a crucial role in cancer...
N-Biotinyl-12-aminododecanoic acid is a biotinylating reagent with an alkane chain connected to a terminal...
Auristatin E (CAS 160800-57-7) disrupts tubulin polymerization, leading to cell cycle arrest and apoptosis....
b-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14 .
nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid...
Paclitaxel CAS:33069-62-4, a natural anticancer agent, stabilizes tubulin polymerization, leading to mitotic arrest...
Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC 50 of 18 μM.
Safingol is the L-threo diastereomer of D-erythro-sphinganine and a dual inhibitor of PKC and sphingosine kinase...
AR-42 (HDAC-42; OSU-HDAC42) is a potent, orally bioavailable pan- HDAC inhibitor ( IC 50 =16 nM). AR-42 induces...
ELA-32(human) is a potent critical cardiac developmental peptide that acts through the G-protein–coupled apelin...
PF-06380101 (Aur0101) CAS:1436391-86-4 is a powerful auristatin microtubule inhibitor derived from the cytotoxic...
Exatecan CAS:171335-80-1 is an innovative camptothecin (CPT) analog that demonstrates powerful topoisomerase-I...
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of...
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