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Cell Death, Autophagy & DNA Damage

Compounds used in apoptosis, autophagy, ferroptosis, cell-cycle and DNA-damage research.

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HY-W0484912′-O-(2-Methoxyethyl)adenosine 168427-74-5 2′-O-(2-Methoxyethyl)adenosine is an ATP ( HY-B2176 ) derivative. 2′-O-(2-Methoxyethyl)adenosine can be used for...
HY-1852723'-O-(2-Nitrobenzyl)-dCTP 959755-19-2 3'-O-(2-Nitrobenzyl)-dCTP is a reversible terminator. 3'-O-(2-Nitrobenzyl)-dCTP can be recognized and incorporated...
HY-168657PARP1/2-IN-4 2093102-22-6 PARP1/2-IN-4 (compound 3) is a PARP1/2 inhibitor.
HY-1321415-PA-dUTP 179101-49-6 5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs)...
HY-112634SIRT5 inhibitor 1 2166487-21-2 SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC 50 of 0.11 μM.
HY-168347TH152 1622917-95-6 TH152 is a reversible, pan ligand for LC3/GABARAP with a K D of 2 µM. LC3/GABARAP is an autophagy associated protein.
HY-118894AB182 54805-58-2 AB-182 is an aziridine derivative and antitumor agent.AB-182 shows synergistic antitumor effects in conjunction with...
HY-176822SGC-BRDVIII-NC 2650530-02-0 SGC-BRDVIII-NC (Compound 35) is a negative control compound of SMARCA2/4 and PB1 bromodomain (BRD) inhibitor....
HY-129425NU1064 dihydrochloride 63916-38-1 NU1064 (dihydrochloride) is an inhibitor of PARP . NU1064 (dihydrochloride) potentiates the cytotoxicity of...
HY-123605CAY10406 2108603-03-6 CAY10406 is an inhibitor for caspase 3/7 . CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without...
HY-N3593Clausine Z 866111-14-0 Clausine Z (1,6-Dihydroxy-9H-carbazole-3-carboxaldehyde) is an alkaloid CDK5 inhibitor isolated from the plant from...
HY-171447LPT99 1263477-83-3 LPT-99 is an antagonist of apoptotic protease activating factor 1 (APAF-1) . LPT-99 suppresses the activation of...
HY-W0484972'-O-MOE-5-Me-rC 244105-55-3 2'-O-MOE-5-Me-rC is an active compound . 2'-O-MOE-5-Me-rC can be used for oligonucleotide synthesis.
HY-N7933STetracosane-d 50 16416-32-3 Tetracosane-d 50 is the deuterium labeled Tetracosane.
HY-N12747Dichlorogelignate 164030-91-5 Dichlorogelignate (compound 4) is a selective inhibitor of topoisomerase II ( Topo II ). Dichlorogelignate has 100%...
HY-145595A(1R,3R)-Ferroptosis inducer-1 2375357-97-2 (1R,3R)-Ferroptosis inducer-1 is an isomer of Ferroptosis inducer-1 ( HY-145595 ). (1R,3R)-Ferroptosis inducer-1...
HY-1390987-Methyl-diguanosine triphosphate 62828-64-2 7-Methyl-diguanosine triphosphate (m7Gp3G) is an mRNA cap structure analog that inhibits in vitro protein synthesis...
HY-113853WF-10129 109075-64-1 WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell...
HY-107314Pulchinenoside B 135247-95-9 Pulchinenoside B is a triterpenoid saponin isolated from Pulsatilla chinensis .
HY-100601PK7242 1446352-68-6 PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In cancer cells carrying the Y220C mutant...

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