Inhibitors, activators and modulators of kinases and phosphorylation pathways.
RG 14921 is a compound structurally related to Erbstatin ( HY-113549 ) and has inhibitory activity against EGFR...
PF-03671148 is an ALK5 inhibitor. PF-03671148 can reduce TGFβ induced fibrotic gene expression in fibroblasts....
Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora...
3-Azetidinemethanol hydrochloride, an intermediate, can be used in the synthesis of SHP2 inhibitor .
WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC 50 of 4 nM for WNK1 .
GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase , with an IC 50 of 29 nM. GSK963 is a...
EphB1-IN-2 is a mutant-selective kinase inhibitor of ABL and FGFR4 , with an IC 50 of 14 nM against ABL G321C mutant...
Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa . Isoprocurcumenol can...
α-Trinositol (PP 56) is an isomer of the intracellular messenger IP3. α-Trinositol can be used in the study of in...
(Z)-Tyrphostin A51 is the Z configuration of Lanoconazole A51. Tyrphostin A51 is a potent protein tyrosine kinase...
WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC 50...
TPKI-39 is a DDR1 , DDR2 , and FLT1 inhibitor, with a human DDR1 IC 50 of 380 nM, human DDR1 K a of 24 nM, human...
Lavendustin C6 is a specific inhibitor of tyrosine kinase . Lavendustin C6 inhibits epidermal growth factor ( EGF )...
Syk-IN-2 (Page 78; 35) is a spleen tyrosine kinase ( Syk ) inhibitor.
SHP2-IN-1 (compound 13) is an allergic inhibitor of SHP2 (PTPN11) , with an IC 50 of 3 nM.
Lck inhibitor 2 is a bisanilino pyrimidine-derived tyrosine kinase inhibitor targeting LCK , BTK , LYN , SYK and TXK...
Nec-34i is an inactive analog structurally similar to Nec-34 ( HY-132203 ). Nec-34i has no effect on RIPK1 kinase...
1,2,3,4-Tetrahydrostaurosporine is a derivative of Staurosporine ( HY-15141 ) and an inhibitor of mutant EGFR ( IC...
SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK.
FP1-24 is a non-selective CK1 kinase inhibitor, with IC 50 values of 40 nM, 10 nM, 10 nM, and 40 nM against human...
日本语
한국어
Français
Deutsch
España
Türkiye