Compounds used in neurological, neuronal and neurodegenerative disease research.
CGS 21680 is a selective adenosine A2A receptor agonist, with a K i of 27 nM.
Tau tracer 1 is a Tau tracer used for imaging Tau protein aggregates. Tau tracer 1 can be used to diagnose...
G194-0712 is a selective histone deacetylase 5 ( HDAC5 ) activator with an EC 50 of 7.96 μM and a K d of 2.53 μM....
MRS1845 is a selective store-operated calcium ( SOC ) channel inhibitor with an IC 50 of 1.7 μM. MRS1845 is an ORAI1...
Nintedanib esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β.
N-Desmethyl-loperamide is a major metabolite of loperamide, a drug that selectively activates peripheral μopioid...
JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 ( mGlu2 ) receptor with an EC 50 of...
Dipyanone hydrochloride is structurally similar to known opioids.
(-)-Gallopamil (hydrochloride) exerts a selective modulation of the fast voltage-dependent inactivation....
Br-PBTC is a potent, 2/4 subtype-selective positive allosteric modulator of nAChRs (nicotinic acetylcholine...
Z-VAD-FMK is a broad spectrum pan-caspase inhibitor that inhibits the intracellular activation of caspase-like...
P2X4-IN-1 (Compound 1) is an orally active P2X4 inhibitor. P2X4-IN-1 can be used in the study of prophylaxis disease.
Etripamil (MSP-2017) is a short-acting, L-type calcium-channel antagonist. Etripamil inhibits calcium influx through...
Lu AE51090 is selective muscarinic M1 receptor agonist with blood-brain barrier penetration. Lu AE51090 activates...
Remeglurant (MRZ-8456) acts as a selective, orally active and allosteric antagonist of the mGlu5 receptor, with an...
Δ9-THC-ethyl is an ethyl-chain homolog of Tetrahydrocannabinol.
KMS88009 is a potent small molecule that directly interferes with the formation of amyloid-β oligomers, thereby...
OGT-IN-4 (compound 4a) is an O-GlcNAc transferase ( OGT ) inhibitor with a K d of 8 nM. OGT-IN-4 can be utilized in...
RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist.
Gamma-secretase modulator 3 is a γ-secretase modulator. Gamma-secretase modulator 3 has the potential for use in...
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