BMS 777607

Overview

BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met , Axl , Ron and Tyro3 with IC 50 s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck , VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.

Application

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Product Information

• Catalog No.: HY-12076
• CAS No.: 1025720-94-8
• Molecular Formula: C25H19ClF2N4O4
• Molecular Weight: 512.89
• Purity: 99.36%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.87 mM); Clear solution
• Availability: In-stock

Source

Original product source