SR1555 hydrochloride is the hydrochloride salt form of SR1555 ( HY-120785 ). SR1555 hydrochloride is an inverse agonist for retinoic acid receptor-related orphan nuclear receptor γ ( RORγ ) with an IC 50 of 1 μM. SR1555 hydrochloride inhibits the development and function of pro-inflammatory TH17 cell, increases the frequency of anti-inflammatory T regulatory (Treg) cells. SR1555 hydrochloride can be used for research about autoimmune diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR
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