1,3-PBIT dihydrobromide

Overview

1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes . Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-120865
• CAS No.: 200716-66-1
• Molecular Formula: C12H20Br2N4S2
• Molecular Weight: 444.25
• Purity: 98%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source