(rac)-AG-205

Overview

(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 ( Pgrmc1 ) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Endocrinology | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-121012
• CAS No.: 442656-02-2
• Molecular Formula: C22H23ClN6OS
• Molecular Weight: 454.98
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source