1,8-Dihydroxy-4,5-dinitroanthraquinone

Overview

1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of serine proteinase NS2B/3 , the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC 50 s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Dengue Virus | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-121138
• CAS No.: 81-55-0
• Molecular Formula: C14H6N2O8
• Molecular Weight: 330.21
• Purity: 98.03%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source