Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO 4 /H 2 O 2 ) with an IC 50 value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine ( HY-111338 )-induced toxicity in human hepatic HepG2 cells with an EC 50 value of 4.02 μM.
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