BKI-1369

Overview

BKI-1369 is a bumped kinase inhibitor (BKI) . BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC 50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-121495
• CAS No.: 1951431-22-3
• Molecular Formula: C23H27N7O
• Molecular Weight: 417.51
• Purity: 99.37%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.98 mM); Clear solution
• Availability: In-stock

Source

Original product source