4-Br-Bnlm

Overview

4-Br-Bnlm is a selective inhibitor of glucose-regulated protein 94 (Grp94) with an EC 50 value of 0.96 µM. 4-Br-Bnlm reduces the levels of mutant myocilin proteins as well as wild-type myocilin misfold in cells. 4-Br-Bnlm promotes the clearance of toxic formsof myocilin and reduces myocilin toxicity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-121845
• CAS No.: 1654775-71-9
• Molecular Formula: C20H18BrClN2O4
• Molecular Weight: 465.72
• Purity: 99.46%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (5.37 mM); Clear solution
• Availability: In-stock

Source

Original product source