Pyr-​Pro-​Arg-​pNA

Overview

Pyr-​Pro-​Arg-​pNA (S-2366) is a chromogenic peptidyl substrate, and a noncompetitive inhibitor that occupies the active sites of FXIa and FXIa-LC to block factor IX activation. Pyr-​Pro-​Arg-​pNA functions as a hydrolyzable substrate for FXIa ’s catalytic domain, human APC , murine APC , and purified plasma kallikrein .

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Crohn's Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Biochemical Assay Reagents | Products > Signaling Pathways > APC | Products > Signaling Pathways > Factor XI

Product Information

• Catalog No.: HY-122142
• CAS No.: 72194-57-1
• Molecular Formula: C22H30N8O6
• Molecular Weight: 502.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source