Melevodopa (Levodopa methylester) is an orally active methylated prodrug of Levodopa ( HY-N0304 ), a dopamine precursor. When used in combination with Carbidopa ( HY-B0311 ) in an effervescent tablet formulation, Melevodopa inhibits motor fluctuations in Parkinson's disease. Melevodopa suppresses subcutaneous tumor growth, pulmonary metastasis proliferation, and primary mass invasiveness of melanoma. Melevodopa induces lipid peroxidation by increasing malondialdehyde levels in melanoma and improves the survival rate of melanoma-bearing mice. Melevodopa can be used in research related to Parkinson's disease (with motor fluctuations) and melanoma.
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