Coprine is an orally active disulfiram ( HY-B0240 )-like component and an inhibitor of aldehyde dehydrogenase . Coprine is isolated from Coprinus atranentarius . Coprine inhibits low K m aldehyde dehydrogenase in rat liver and increases blood acetaldehyde levels during in vivo ethanol metabolism. Coprine does not inhibit semi-purified low K m aldehyde dehydrogenase from rat liver in vitro. Coprine can be used in studies related to alcoholism.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Aldehyde Dehydrogenase (ALDH) | Products > Signaling Pathways > Drug Derivative
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