BETi-211 is an orally active BET inhibitor ( K i : <1 nM). BETi-211 inhibits growth of triple-negative breast cancers (TNBC) cell lines with IC 50 < 1 μM. BETi-211 degrades BET proteins and suppress tumor growth in xenograft breast tumors.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > Ligands for Target Protein for PROTAC
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