Rostafuroxin

Overview

Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na + ,K + -ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus ( RSV )-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity.

Application

Products | Products > Disease Areas > Hypertension | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Na+/K+ ATPase | Products > Signaling Pathways > RSV

Product Information

• Catalog No.: HY-12283
• CAS No.: 156722-18-8
• Molecular Formula: C23H34O4
• Molecular Weight: 374.51
• Purity: 98.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.68 mM); Clear solution
• Availability: In-stock

Source

Original product source