3-Fluoroacetanilide

CAS No.：351-28-0

Other grades of this product :

3-Fluoroacetanilide Basic information

Product Name:	3-Fluoroacetanilide
Synonyms:	N-(3-Fluorophenyl)acetamide, N-Acetyl-3-fluoroaniline;3-Acetamido-1-fluorobenzene N-(3-Fluorophenyl)acetamide;N-Acetyl-3-fluoroaniline;Acetamide, N-(3-fluorophenyl)-;Acetanilide, 3'-fluoro-;3-ACETAMIDO-1-FLUOROBENZENE;3'-FLUOROACETANILIDE;3-FLUOROACETANILIDE
CAS:	351-28-0
MF:	C8H8FNO
MW:	153.15
EINECS:	206-509-6
Product Categories:	Anilines, Amides & Amines;Fluorine Compounds;Nitrogen Compounds;Organic Building Blocks;Protected Amines
Mol File:	351-28-0.mol

3-Fluoroacetanilide Chemical Properties

Melting point	82-84 °C(lit.)
Boiling point	293.3±23.0 °C(Predicted)
density	1.1655 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	methanol: soluble25mg/mL, clear, colorless to yellow
pka	14.34±0.70(Predicted)
form	powder to crystal
color	White to Light yellow
Water Solubility	insoluble
BRN	2803073
CAS DataBase Reference	351-28-0(CAS DataBase Reference)
NIST Chemistry Reference	3'-Fluoroacetanilide(351-28-0)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39-36
WGK Germany	3
HazardClass	IRRITANT
HS Code	29242990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

3-Fluoroacetanilide Usage And Synthesis

Chemical Properties	off-white crystalline powder
Uses	3''-Fluoroacetanilide is a reactant in the preparation of trifluoromethylaryl acetamides via Pd-catalyzed trifluoromethylation of aromatics C-H bond with Umemoto''s reagent directed by acetamino group.

3-Fluoroacetanilide Preparation Products And Raw materials

Raw materials	Diethyl ether-->Acetic acid-->Magnesium sulfate-->Acetic anhydride-->3-Fluoroaniline-->3-Fluorophenyl azide solution-->3-Fluoro-2-methylaniline-->3-FLUOROPHENYLACETYLENE-->Tungsten hexacarbonyl-->Thioacetic acid-->Ethyl acetate-->Acetyl chloride-->3'-Fluoroacetophenone
Preparation Products	4''-CHLORO-2''-FLUOROACETOPHENONE-->3-Fluoro-4-nitroaniline-->2,4-DICHLORO-5-FLUOROANILINE

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