AP-22161

Overview

AP22161 is a potent and selective Src SH2 domain inhibitor with an IC 50 of 0.24 µM. AP22161 exhibits >120-fold selectivity over Yes SH2 ( IC 50 = 29.38 µM) and ZAP SH2 ( IC 50 = 421.86 µM). AP22161 inhibits Src-dependent cellular activity and diminishes osteoclast resorptive activity. AP22161 can be used for osteoporosis research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Mineral Metabolism | Products > Disease Areas > Osteoporosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-123394
• CAS No.: 268741-42-0
• Molecular Formula: C32H39N3O7
• Molecular Weight: 577.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source