JNJ-42253432

Overview

JNJ-42253432 is a CNS-penetrant, high-affinity and orally active P2X7 antagonist, with pK i values of 9.1 and 7.9 for rat and human P2X7 channels, respectively.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > P2X Receptor

Product Information

• Catalog No.: HY-123481
• CAS No.: 1428327-35-8
• Molecular Formula: C28H38N4O
• Molecular Weight: 446.63
• Purity: 98.15%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution
• Availability: In-stock

Source

Original product source