Clorobiocin is an antibacterial agent with an IC 50 of 0.21 μM against the B subunit of E. coli DNA gyrase . Clorobiocin targets the mLaC protein of Gram-negative bacteria. Clorobiocin potently inhibits bacterial DNA replication. Clorobiocin can be used in studies on Gram-negative bacterial infections, such as Acinetobacter baumannii and E. coli infections.
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