FSBA (5'-p-Fluorosulfonylbenzoyladenosine) hydrochloride is a covalent modifier and affinity labeling reagent for adenine nucleotide-binding proteins . FSBA hydrochloride covalently attaches to the nucleotide-binding sites of pyruvate kinase , glutamate dehydrogenase , and p56 lck , and to a lysine residue in the ATP-binding site of cAMP-dependent protein kinase , causing loss of enzymatic activity. FSBA hydrochloride can be used for the research of T lymphoma.
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