R-138727

Overview

R-138727, the major active metabolite of Prasugrel ( HY-15284 ), is a highly potent and selective irreversible antagonist of the P2Y12 receptor , with an IC 50 of 2.5 μM. R-138727 covalently binds to the P2Y12 receptor on the platelet surface, blocking adenosine diphosphate-mediated platelet activation and aggregation. R-138727 can be used to study stroke, cerebral infarction and neurological deficits.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > P2Y Receptor | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-123669
• CAS No.: 204204-73-9
• Molecular Formula: C18H20FNO3S
• Molecular Weight: 349.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source