KIN1400

Overview

KIN1400 is a potent IRF3 activator. KIN1400 triggers IRF3-dependent innate immune antiviral genes ( RIG-I, MDA5, IFIT1 , and Mx1 ) and IFN-β expression. KIN1400 inhibits WNV and DV , two mosquito-borne members of the Flaviviridae and the genus Flavivirus . KIN1400 also inhibits HCV replication. KIN1400 induces innate antiviral immunity through a MAVS-IRF3 axis.

Application

Products | Products > Disease Areas > Viral Infection | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Hepatitis Virus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > RIG-I-like receptor (RLR) | Products > Signaling Pathways > HCV | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-123805
• CAS No.: 446826-86-4
• Molecular Formula: C24H17F2N3O2S
• Molecular Weight: 449.47
• Purity: 98.1%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source