KIN1400

CAS No.：446826-86-4
Grade：98.1%
Formula：C24H17F2N3O2S
M.W.：449.47

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

KIN1400 is a potent IRF3 activator. KIN1400 triggers IRF3-dependent innate immune antiviral genes ( RIG-I, MDA5, IFIT1 , and Mx1 ) and IFN-β expression. KIN1400 inhibits WNV and DV , two mosquito-borne members of the Flaviviridae and the genus Flavivirus . KIN1400 also inhibits HCV replication. KIN1400 induces innate antiviral immunity through a MAVS-IRF3 axis.

Application

Products | Products > Disease Areas > Viral Infection | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Hepatitis Virus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > RIG-I-like receptor (RLR) | Products > Signaling Pathways > HCV | Products > Signaling Pathways > IFNAR

Product Information

Catalog No.: HY-123805
CAS No.: 446826-86-4
Molecular Formula: C24H17F2N3O2S
Molecular Weight: 449.47
Purity: 98.1%
Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Availability: In-stock

Source

Original product source

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