HG-12-6 is a type II inhibitor of IRAK4 . HG-12-6 shows preferential binding to unphosphorylated inactive IRAK4 with an IC 50 of 165 nM. HG-12-6 can modulate IRAK4 activity in autoimmunity and inflammation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IRAK
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