TEI-9647

Overview

TEI-9647, a Vitamin D 3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH) 2 D 3 . TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH) 2 D 3 . TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > VD/VDR

Product Information

• Catalog No.: HY-12398
• CAS No.: 173388-20-0
• Molecular Formula: C27H38O4
• Molecular Weight: 426.59
• Purity: 99.10%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: 2.5 mg/mL (5.86 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source