Talfirastide acetate

Overview

Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system ( RAS ) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity ( IC 50 =0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium.

Application

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Product Information

• Catalog No.: HY-12403A
• CAS No.: 2855063-75-9
• Molecular Formula: C43H66N12O13
• Molecular Weight: 959.06
• Purity: 99.76%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 100 mg/mL (104.27 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source