8-Deazahomofolic acid

8-Deazahomofolic acid
  • CAS No.:111113-73-6
  • Grade:99.98%
  • Formula:C21H22N6O6
  • M.W.:454.44

Overview

8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes . 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX ( HY-14519 ) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC 50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Signaling Pathways > Thymidylate Synthase | Products > Signaling Pathways > Bacterial

Product Information

  • Catalog No.: HY-124093
  • CAS No.: 111113-73-6
  • Molecular Formula: C21H22N6O6
  • Molecular Weight: 454.44
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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