GPI-1046

Overview

GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus ( HIV )-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > Depression | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > EAAT | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-124619
• CAS No.: 186452-09-5
• Molecular Formula: C20H28N2O4
• Molecular Weight: 360.45
• Purity: 99.79%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1 mg/mL (2.77 mM); Clear solution
• Availability: In-stock

Source

Original product source