BI-4464

Overview

BI-4464 is a highly selective, ATP competitive PTK2/FAK protein kinase inhibitor with an IC 50 value of 17 nM. BI-4464 is a FAK ( HY-43760 ) ligand and linker conjugate. BI-4464 can be used to construct proteolysis targeting chimeras ( PROTACs ), such as PROTAC FAK degrader 4 ( HY-178467 ). PROTAC FAK degrader 4 is a highly potent and selective FAK PROTAC degrader.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Signaling Pathways > FAK | Products > Signaling Pathways > Target Protein Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-124625
• CAS No.: 1227948-02-8
• Molecular Formula: C28H28F3N5O4
• Molecular Weight: 555.55
• Purity: 98.64%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source