S1PL-IN-2 (Compound 28) is a potent sphingosine-1-phosphate lyase ( S1PL ) inhibitor with an IC 50 of 120 nM. S1PL-IN-2 shows an IC 50 of 230 nM on HEK293 cells. S1PL-IN-2 block the conversion of Vitamin B6 into the active pyridoxal-4-phosphate cofactor required for S1P lyase activity. S1PL-IN-2 can be used for the researches of inflammation and immunology, such as rheumatoid arthritis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.