Pyrimidinone 8

Overview

Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 ( DMT1 ), with a K i of 20 μM ( hDMT1 ). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1 -mediated iron uptake, with an IC 50 of 13.8 μM.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Others | Products > Signaling Pathways > Ferroportin

Product Information

• Catalog No.: HY-124703
• CAS No.: 65004-42-4
• Molecular Formula: C10H12N4O
• Molecular Weight: 204.23
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source