Vps34-IN-2

Overview

Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC 50 s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively. Vps34-IN-2 shows antiviral activity against SARS-CoV-2 ( IC 50 of 3.1 μM), HCoV-229E ( IC 50 of 0.7 μM) and HCoV-OC43 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-12473
• CAS No.: 1523404-29-6
• Molecular Formula: C18H25F3N4O3
• Molecular Weight: 402.41
• Purity: 99.73%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.21 mM); Clear solution
• Availability: In-stock

Source

Original product source