SBI-425 is an orally active and potent TNAP ( tissue-nonspecific alkaline phosphatase ) inhibitor ( IC 50 =16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phosphatase
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