Col003

Overview

Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 ( IC 50 =1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-124817
• CAS No.: 328565-16-8
• Molecular Formula: C14H11NO4
• Molecular Weight: 257.24
• Purity: 99.46%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: 2.5 mg/mL (9.72 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source