L-162782

Overview

L-162782 is a high affinity AT 1 receptor ligand for rat and human wild-type AT 1 with IC 50 values of 28.5 and 24.6 nM, respectively. L-162782 acts as a partial agonist ( EC 50 ≈ 30 nM) and insurmountable antagonist ( IC 50 = 6.5 μM) on wild-type rat AT 1 receptors in COS-7 cells. L-162782 reduces Angiotensin II ( HY-13948 )-induced phosphatidylinositol turnover. L-162782 can be used for hypertension research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor

Product Information

• Catalog No.: HY-125094
• CAS No.: 169281-92-9
• Molecular Formula: C32H40N4O4S
• Molecular Weight: 576.76
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source