DNS-pE

Overview

DNS-pE is a 3-phosphoglycerate dehydrogenase ( PHGDH ) inhibitor with a K i of 7.4 μM. DNS-pE selectively and irreversibly covalently modifies endogenous PHGDH in live mammalian cells, its vinyl sulfone moiety acts as a fluorescence quencher that becomes highly fluorescent upon covalent modification of PHGDH. DNS-pE can be used as a fluorescent dye for live-cell imaging.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Phosphoglycerate Dehydrogenase (PHGDH)

Product Information

• Catalog No.: HY-125273
• CAS No.: 2196245-98-2
• Molecular Formula: C14H15NO2S
• Molecular Weight: 261.34
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source