DS42450411 is an orally active hepcidin production inhibitor with an IC 50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6 , DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Ferroportin
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