NV03 is a potent and selective antagonist of Ubiquitin-like with PHD and RING finger domains 1 ( UHRF1 )-H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 is also a ligand for E3 ligase . NV03 can be studied in anticancer research.
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