PSB-1737

Overview

PSB-1737 is a human-selective GPR17 agonist with an EC 50 for human GPR17 of 270 nM, and its activity on murine GPR17 is relatively weak ( EC 50 > 10 μM). PSB-1737 shows no significant inhibition at the glycine binding site of NMDA receptors, and has no significant agonistic or antagonistic activity on P2Y receptor subtypes. PSB-1737 can be used in demyelinating diseases (such as multiple sclerosis) or inflammatory-related anemia.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Orphan GPCR

Product Information

• Catalog No.: HY-125313
• CAS No.: 139896-80-3
• Molecular Formula: C18H15NO5
• Molecular Weight: 325.32
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source