Ro 25-0534 is an antimicrobial compound against Pseudomonas. Ro 25-0534 is active against Enterobacteriaceae (MIC 90 : 0.06-2 μg/mL), Oxacillin ( HY-B0465 )-susceptible staphylococci , β-hemolytic streptococci, and penicillin-susceptible pneumococci (MIC 90 : 1-2 μg/mL), Haemophilus influenzae (MIC 90 : 0.25-0.5 μg/mL), Moraxella catarrhalis (MIC 90 : 0.5 μg/mL), and most nonenteric Gram-negative bacilli (MIC 90 : 2-4 μg/mL).
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