(rac)-AR-13503

Overview

(rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) is the isoform of AR-13503 ( HY-12798C ). AR-13503 a ROCK/PKC inhibitor, inhibiting angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. AR-13503 also inhibits the formation of aberrant neovascularization (NV) in oxygen-induced retinopathy (OIR) model in mice.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > PKC | Products > Signaling Pathways > ROCK

Product Information

• Catalog No.: HY-125639
• CAS No.: 1254032-16-0
• Molecular Formula: C19H19N3O2
• Molecular Weight: 321.37
• Purity: 99.08%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 4 mg/mL (12.45 mM); Clear solution
• Availability: In-stock

Source

Original product source