Pseudouridimycin

Overview

Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP) , with an IC 50 of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis.

Application

Products | Products > Disease Areas > Streptococcus Pyogenes Infection | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog

Product Information

• Catalog No.: HY-125650
• CAS No.: 1566586-52-4
• Molecular Formula: C17H26N8O9
• Molecular Weight: 486.44
• Purity: 96.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source