Ucf-101

Overview

Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2 , with an IC 50 of 9.5 μM for His-Omi . Ucf-101 exhibits very little activity against various other serine proteases (IC 50 >200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect.

Application

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Product Information

• Catalog No.: HY-125959
• CAS No.: 313649-08-0
• Molecular Formula: C27H17N3O5S
• Molecular Weight: 495.51
• Purity: 99.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 1.79 mg/mL (3.61 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source