Dooku1

Overview

Dooku1 is a reversibly Yoda1 antagonist with IC 50 value of 1.3 μM and 1.5 μM for 2 μM Yoda1-induced Ca 2+ entry HEK 293 cells and HUVECs, respectively. Dooku1 can disrupt Yoda1-induced Piezo1 channel activity and inhibit Yoda1-induced relaxation of aorta. Dooku1 can be used for vascular physiology and disease research .

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Others | Products > Signaling Pathways > Piezo Channel

Product Information

• Catalog No.: HY-126010
• CAS No.: 2253744-54-4
• Molecular Formula: C13H9Cl2N3OS
• Molecular Weight: 326.20
• Purity: 99.90%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (6.38 mM); Clear solution
• Availability: In-stock

Source

Original product source