PAT-347 is an inhibitor of autotaxin ( ATX , ENPP-2 ). PAT-347 binds only to the hydrophobic channel of ATX , without occupying its hydrophobic pocket and catalytic site. PAT-347 blocks the binding of lysophosphatidylcholine (LPC) to the catalytic site of ATX .
Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Phosphodiesterase (PDE)
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