NPD-1335

NPD-1335
  • CAS No.:2376326-31-5
  • Grade:98.10%
  • Formula:C28H29N3O3
  • M.W.:455.55

Overview

NPD1335 is a Trypanosoma brucei phosphodiesterase B1 ( TbrPDEB1 ) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. NPD-1335 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Parasite

Product Information

  • Catalog No.: HY-126250
  • CAS No.: 2376326-31-5
  • Molecular Formula: C28H29N3O3
  • Molecular Weight: 455.55
  • Purity: 98.10%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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